"accession"	"counters"	"description"	"gene"	"go_terms"	"id"	"ida_accession"	"in_alphafold"	"in_bfvd"	"is_fragment"	"length"	"name"	"protein_evidence"	"proteome"	"sequence"	"source_database"	"source_organism"
"A0A485PDH1"	"{'domain_architectures': 20686, 'entries': 14, 'isoforms': 0, 'proteomes': 1, 'sets': 2, 'structures': 0, 'taxa': 1, 'dbEntries': {'cathgene3d': 2, 'profile': 1, 'smart': 1, 'cdd': 1, 'ssf': 2, 'pfam': 1, 'panther': 1, 'interpro': 5}, 'proteome': 1, 'taxonomy': 1, 'similar_proteins': 20686}"	"['Cytoplasmic adapter protein that plays a critical role in clathrin-mediated endocytosis which is important in processes such as internalization of cell receptors, synaptic transmission or removal of apoptotic cells. Recruits AP-2 and attaches clathrin triskelions to the cytoplasmic side of plasma membrane leading to clathrin-coated vesicles (CCVs) assembly. Furthermore, regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature. In addition to binding to clathrin, mediates the endocytosis of small R-SNARES (Soluble NSF Attachment Protein REceptors) between plasma membranes and endosomes including VAMP2, VAMP3, VAMP4, VAMP7 or VAMP8. In turn, PICALM-dependent SNARE endocytosis is required for the formation and maturation of autophagic precursors. Modulates thereby autophagy and the turnover of autophagy substrates such as MAPT/TAU or amyloid precursor protein cleaved C-terminal fragment (APP-CTF)']"	"LYPA_23C005018"	"[{'identifier': 'GO:0005543', 'name': 'phospholipid binding', 'category': {'code': 'F', 'name': 'molecular_function'}}, {'identifier': 'GO:0005545', 'name': '1-phosphatidylinositol binding', 'category': {'code': 'F', 'name': 'molecular_function'}}, {'identifier': 'GO:0030276', 'name': 'clathrin binding', 'category': {'code': 'F', 'name': 'molecular_function'}}, {'identifier': 'GO:0048268', 'name': 'clathrin coat assembly', 'category': {'code': 'P', 'name': 'biological_process'}}, {'identifier': 'GO:0030136', 'name': 'clathrin-coated vesicle', 'category': {'code': 'C', 'name': 'cellular_component'}}, {'identifier': 'GO:0072583', 'name': 'clathrin-dependent endocytosis', 'category': {'code': 'P', 'name': 'biological_process'}}]"	"A0A485PDH1_LYNPA"	"9552d3e056c56f6fe46d99bc0a18241f3abe1baa"	True	False	False	660	"Phosphatidylinositol-binding clathrin assembly protein"	3	"UP000386466"	"MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVLPMPSTSQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLPISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQSLPVAKLPPNKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM"	"unreviewed"	"{'taxId': '191816', 'scientificName': 'Lynx pardinus', 'fullName': 'Lynx pardinus (Iberian lynx)'}"