{"metadata":{"accession":"A0A452SAI5","id":"A0A452SAI5_URSAM","source_organism":{"taxId":"9643","scientificName":"Ursus americanus","fullName":"Ursus americanus (American black bear)"},"name":"Nuclear receptor subfamily 0 group B member 1","description":["Nuclear receptor that lacks a DNA-binding domain and acts as a corepressor that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency"],"length":471,"sequence":"MAGEDHQWQGSILYNMLMSAKQMHAAPEAPEARLGGTCWGCSCGSEPPVGREGLPGGRAVTLLYRCCFCGEDHPRQGSILYNMLTSAKQTHAAPEAPEARLGGACWGCSCGSEPPVSREGLPAGRTTALLYRCCFCGEDHPRQGSILYSLLTSAKQTHVAPEAPEARPGGVWWDRSYSAQGLGGRGELPGGQAVALLYRCCFCGEDHPGQGSILHHLPTSAKQTHGAPETQPAAPWWDPQCGAQRPVALKNPQVVCEAAAAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWAPLLMLELAQDRLNFETVETSEPSLLQRILTTRRRETAGDEPPPLSPLQPPSAPPPEAGHLPSAAEVQAIKCFLAKCWSLDISTKEYAYLKGTVLFNPDLPGLQCVKYIQGLQWGTQQILSDHIRMTHRRYQARFAELNSALFLLRFINANVIVELFFRPIIGSVSMDDMMLEMLCAKL","proteome":"UP000291022","gene":"NR0B1","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"ae17a3629d864651877d789023c58b8c756f1cad","counters":{"domain_architectures":9,"entries":14,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"profile":1,"ssf":1,"cdd":1,"cathgene3d":1,"pfam":2,"smart":1,"panther":1,"prints":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":9}}}