{"metadata":{"accession":"A0A452EE06","id":"A0A452EE06_CAPHI","source_organism":{"taxId":"9925","scientificName":"Capra hircus","fullName":"Capra hircus (Goat)"},"name":"Cytochrome P450","description":["Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics"],"length":494,"sequence":"MGLLSGDMLGPLAVAVLIFLLLLDVMHRRSRWAPRYPPGPTPLPVLGNLLQVDFEDPRPSFNQLRRRFGNVFSLQQVWTPVVVLNGLAAVREALVYRNQDTSDRPPPAVYEHVGYGPRAEGVILARYGKAWREQRRFSLSTLRNFGLGKKSLEQWVTEEASCLCAAFADQAGRPFSPRDLLNKAVSNVIASLTFGFRFEYNDPRIVKLLDMMEDMLKEESGLVRQVSVEAASVLQQIFPGLKAFMALIDELITEQKMTRDPTQPPRHLIDAFLDEVKEAKGNPESSFNDENLRLVVTDLFSAGMVTTSTTLAWALLLMILHPDVQRRVQQEIDEVIGKVRRPEMGDQALMPFTVAVVHEVQRFADIIPLGLPHMTSRDIEVQGFYVPKGTTLITNLSSVLKDETIWEKPFCFHPEHFLDAQGRFVKQEAFIPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPAGQPRPSDHGVFAFLVTPPPYQLCAVPR","proteome":"UP000291000","gene":"CYP2D6","go_terms":[{"identifier":"GO:0004497","name":"monooxygenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005506","name":"iron ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016705","name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0020037","name":"heme binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016712","name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"a02e61ba6c64bb9a9c779746e03a6c43264a16fb","counters":{"domain_architectures":520850,"entries":15,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"pfam":1,"ssf":1,"cdd":1,"panther":1,"prints":3,"prosite":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":520850}}}