{"metadata":{"accession":"A0A429ZBW4","id":"A0A429ZBW4_9ENTE","source_organism":{"taxId":"2739","scientificName":"Vagococcus salmoninarum","fullName":"Vagococcus salmoninarum"},"name":"Multifunctional fusion protein","description":["Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation","Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions"],"length":462,"sequence":"MRHDQRKEAELRQITIETNVLKHPEGSVLVSFGDTKVLCAATFEDKVPPFLRGGGTGWVTAEYSMLPRATHTRNIRESAKGKLSGRTMEIQRLIGRALRSVVDLEVLGERSLVVDCDVIQADGGTRTASITGAFVALSLAVEKLLKDGTLTESPLKEHLAAVSVGILPSGEAVLDLDYIEDSSALVDMNLVMTEAGQFVEIQGTGEEATFSTEELTAMLSLGKSGISELIAEQKNVLRASQRAAKGTNDPKTADNQLLIATRNPGKAKEFQKLFAGQGLIIKTLLDYPEIPDVPETATTFEGNARLKAETIAAELNCLVLADDSGLKVAALGGQPGVYSARFAGEGKSDNANNAKLLHELTDVKAEERQASFHCTLVLAAPGRKSLVVSGEIAGRIVTIPQGENGFGYDPLFLVEEKGQTMAELSDEVKNQISHRGIAIQELSQQWSAWLENEAENELFSSK","proteome":"UP000287239","gene":"rph","go_terms":[{"identifier":"GO:0000049","name":"tRNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009022","name":"tRNA nucleotidyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008033","name":"tRNA processing","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0047429","name":"nucleoside triphosphate diphosphatase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009143","name":"nucleoside triphosphate catabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0017111","name":"ribonucleoside triphosphate phosphatase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"c557d2c10ef07d9d58d40a9df636256d992255b0","counters":{"domain_architectures":347,"entries":28,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"ssf":3,"cathgene3d":2,"pfam":3,"cdd":2,"panther":1,"ncbifam":3,"hamap":2,"prosite":1,"interpro":11},"proteome":1,"taxonomy":1,"similar_proteins":347}}}