{"metadata":{"accession":"A0A3Q7NLD4","id":"A0A3Q7NLD4_CALUR","source_organism":{"taxId":"34884","scientificName":"Callorhinus ursinus","fullName":"Callorhinus ursinus (Northern fur seal)"},"name":"NAD(P)H oxidoreductase RTN4IP1, mitochondrial","description":["NAD(P)H oxidoreductase involved in the ubiquinone biosynthetic pathway. Required for the O-methyltransferase activity of COQ3. Able to catalyze the oxidoreduction of 3-demethylubiquinone into 3-demethylubiquinol in vitro. However, it is unclear if 3-demethylubiquinone constitutes a substrate in vivo. May also play a role in the regulation of retinal ganglion cell (RGC) neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury"],"length":399,"sequence":"MFTMEFLKTCVLGRNACTAVCFWRSHAVQRLLVGKISTTSSRSTVMPAWVIDRYGKNDVLRFTQNMMIPVIHYPNEVVIKVHAASVNPIDVNMRSGYGATALNMKRDPLHIKTKGEEFPLTLGRDVSGVVMECGLDVRYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSLKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKHVLILGASGGVGTFAIQVMKAWGANVTAVCSQDASELVRKLGADDVIDYKSGNVEEQLKSLKPFDFILDNVGGSTETWALNFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWQGVHYRWAFFMASGVYLDDIAKLVDEGKIQPVIEKTFPFSQVPEAFLKVERGHARGKTVINVI","proteome":"UP000286641","gene":"RTN4IP1","go_terms":[{"identifier":"GO:0005739","name":"mitochondrion","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0016491","name":"oxidoreductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008270","name":"zinc ion binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"37218a30e19a1dc4f38eb3bfb201e6a6601db95e","counters":{"domain_architectures":59802,"entries":17,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"cdd":1,"cathgene3d":2,"smart":1,"pfam":2,"panther":1,"prosite":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":59802}}}