{"metadata":{"accession":"A0A3Q7NAJ8","id":"A0A3Q7NAJ8_CALUR","source_organism":{"taxId":"34884","scientificName":"Callorhinus ursinus","fullName":"Callorhinus ursinus (Northern fur seal)"},"name":"NADPH:adrenodoxin oxidoreductase, mitochondrial","description":["Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Also acts as a ferredoxin--NADP(+) reductase essential for coenzyme Q biosynthesis: together with FDX2, transfers the electrons required for the hydroxylation reaction performed by COQ6"],"length":514,"sequence":"MPPQRARGVSGILSSGRLLFQAMAPRCWRWWHWSAWRRTRPPPAGSTPSFRQQFSTQEQPPQICVVGSGPAGFYTAQHLLKHHPRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQTARLDRCAFRGNVVVGRDVAVSELRAAYHAVVLSYGAEDHQALEIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPEHLEKTDITEAALGVLRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPILDPADFLGLQDRIKEVPRQRKRLTELLLRTATEKPGVEEAARQALASCTWGLRFFRSPQRVLPSPDGRRVAGIRLAVTRLEGVGEAARAAPTGDTEDLPCGLVLSSVGYKSRPIDPSVPFDPKLGVIPNMEGRVIDVPGLYCSGWVKRGPTGVIATTMTDSFLTGQMLLQDLKAGLLPSGPRPGYAAIEALLSSRGVRPVSFSDWEKLDAEEVSRGKGAGKPREKLLDPQEMLRLLGR","proteome":"UP000286641","gene":"FDXR","go_terms":[{"identifier":"GO:0016491","name":"oxidoreductase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"9495317de2963efe281f3cfa4c7282a72b89ba56","counters":{"domain_architectures":111992,"entries":12,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"pfam":1,"cathgene3d":2,"pirsf":1,"panther":1,"prints":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":111992}}}