{"metadata":{"accession":"A0A3P9C0N6","id":"A0A3P9C0N6_9CICH","source_organism":{"taxId":"106582","scientificName":"Maylandia zebra","fullName":"Maylandia zebra (zebra mbuna)"},"name":"Anaphase-promoting complex subunit 11","description":["Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins. May recruit the E2 ubiquitin-conjugating enzymes to the complex"],"length":94,"sequence":"MRLCSCQIRRMKVKIKQWNGVASWLWVANDDNCGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLNSQQVQQQCPMCRQEWKFKE","proteome":"UP000265160","gene":null,"go_terms":[{"identifier":"GO:0008270","name":"zinc ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0061630","name":"ubiquitin protein ligase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0097602","name":"cullin family protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0031145","name":"anaphase-promoting complex-dependent catabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005680","name":"anaphase-promoting complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"4413c68b229aca9bf8d0fab9eb370c1f77d8b15c","counters":{"domain_architectures":3293,"entries":10,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"cdd":1,"pfam":1,"profile":1,"panther":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":3293}}}