{"metadata":{"accession":"A0A3B1JXJ9","id":"A0A3B1JXJ9_ASTMX","source_organism":{"taxId":"7994","scientificName":"Astyanax mexicanus","fullName":"Astyanax mexicanus (Blind cave fish)"},"name":"Tubulin gamma chain","description":["Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation"],"length":451,"sequence":"MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHTILNSPYANLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLEKLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFDRTCRQYDKLRKREAFLEQFRKEDIFKDNFDELDNSREVVQQLIDEYSAATRPDYISWGTQEQ","proteome":"UP000018467","gene":null,"go_terms":[{"identifier":"GO:0007020","name":"microtubule nucleation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0031122","name":"cytoplasmic microtubule organization","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0000930","name":"gamma-tubulin complex","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0005525","name":"GTP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007017","name":"microtubule-based process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005874","name":"microtubule","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"9b3c3afba4e26bfbe1001f745b27d736c962bd9e","counters":{"domain_architectures":44972,"entries":23,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"ssf":2,"cdd":1,"pfam":2,"smart":2,"panther":1,"prints":2,"prosite":1,"interpro":9},"proteome":1,"taxonomy":1,"similar_proteins":44972}}}