{"metadata":{"accession":"A0A3B1JLJ8","id":"A0A3B1JLJ8_ASTMX","source_organism":{"taxId":"7994","scientificName":"Astyanax mexicanus","fullName":"Astyanax mexicanus (Blind cave fish)"},"name":"Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3","description":["Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce iron cations Fe(3+) into Fe(2+) in the lumen of the late endosome and lysosome. Reduced iron can then be extruded from the late endosome and lysosome to the cytoplasm by divalent metal-specific transporters. It is therefore most probably involved in endosomal and lysosomal cellular iron homeostasis"],"length":247,"sequence":"MKGTVAFYTAHLLCLVLSVVCVVLVVYWNSSYRGGFAWDHKAKQFNWHPVLMVLGLVVLYGNAAVVYRIPLTWGQNKLPWKLLHAGLLLLSLIFAVVGLCAVFDFHNAGNTPNLYSLHSWVGITTTVLFAMQWAAGFGAFLLPCSPMALRVFVKPAHVWMGSTILVLSVVSCISGINEKLFFVLKKSTNGTHSYAELPAEAVLANSLGVVIVAFALVVLKILANQSWRRPDPRSEEGEYRSLRTDEH","proteome":"UP000018467","gene":null,"go_terms":[{"identifier":"GO:0016491","name":"oxidoreductase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"3a3c8a2abb46469df3e9f07ea0ffd1238f32eaca","counters":{"domain_architectures":13551,"entries":7,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"profile":1,"smart":1,"panther":1,"pfam":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":13551}}}