{"metadata":{"accession":"A0A384B960","id":"A0A384B960_BALAC","source_organism":{"taxId":"9767","scientificName":"Balaenoptera acutorostrata","fullName":"Balaenoptera acutorostrata (Common minke whale)"},"name":"Tissue factor pathway inhibitor","description":["Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma"],"length":253,"sequence":"MIDAMKKEQIFCVSVCLLLSCASAPLNAVPEEDEEHTNITDAELPPLKLVHSFCALKADDGPCKAMIKRFFFNIHTQQCEEFIYGGCEGNQNRFESLEECKEKCTRDYPKKTRRTKTTLQKEKPDFCFLEEDAGICRGYITRYFYNNQSKQCERFKYGGCLGNLNNFESLEECKDTCEDTLNDFQVDDYRTQLGAVNNDSLTPQPTKVPSFFVTTGRTNDGWKNADHTYQVFLNICIHASIFILRLHRILCIC","proteome":"UP001652580","gene":"TFPI","go_terms":[{"identifier":"GO:0004867","name":"serine-type endopeptidase inhibitor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0030414","name":"peptidase inhibitor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0010466","name":"negative regulation of peptidase activity","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005576","name":"extracellular region","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"11460c335ee125c943cebfa6d20b4d8e96495158","counters":{"domain_architectures":3295,"entries":17,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"profile":2,"cathgene3d":1,"ssf":1,"cdd":2,"smart":1,"pfam":1,"panther":1,"pirsf":1,"prosite":1,"prints":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":3295}}}