{"metadata":{"accession":"A0A368VHQ4","id":"A0A368VHQ4_9ACTN","source_organism":{"taxId":"1500506","scientificName":"Halopolyspora algeriensis","fullName":"Halopolyspora algeriensis"},"name":"Multifunctional fusion protein","description":["APS kinase catalyzes the synthesis of activated sulfate","Catalyzes the synthesis of activated sulfate","With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD"],"length":639,"sequence":"MTEDVRNSVYEADRLIAEDIDAYLEQHQHKSLLRFITCGSVDDGKSTLIGRLLYDSKLIFEDQLAELEADSKRVGTQGQDSDLALLVDGLVAEREQGITIDVAYRFFATEKRKFIVADTPGHEQYTRNMVTGASTADVAVILVDARKGVLTQTRRHSYLAQLMGVRHIVLAVNKMDLVGYNRAIFDAIVAEYTEFAESIDLTDVTAIPISALAGDNVAARSDNTPWYEGLALIPVLESVQVGDAFDHGAAFRMPVQWVNRPSHDFRGFAGLIASGSVGVGDPVRILPSGRTSTVARIVTFDGDLDRGLAGQSVTITLTEEEDCSRGDVIAAADDSPAVSDGFEVMLVWMAEEPMLPGRPYWLKIGTQTVTATIQSPKYQVDVNTMEQQPAKTLSLNAIGVANLSTDRSIVFEPYRKDPALGGFVLMDKLTNTTVAAGMLHFALRRAENVHWQAIEVSRDAHAQQKNQRPKVVWFTGLSGSGKSTIANLVEKRLHALGKHCFLLDGDNIRHGLNKDLGFTDADRVENIRRVGEVAKLLTDAGLIAIAAFISPFEAERIMLRDMMEPGEFVEIHVDTTLAEAERRDVKGLYAKARAGKLPNFTGVDSPYEPPANPDLRIDTIATTPEDAAATIVDLILQDR","proteome":"UP000253495","gene":"cysN","go_terms":[{"identifier":"GO:0003924","name":"GTPase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005525","name":"GTP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006790","name":"sulfur compound metabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0004020","name":"adenylylsulfate kinase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000103","name":"sulfate assimilation","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"0865e74123f80960853311c8d65aea0bb5723cee","counters":{"domain_architectures":3803,"entries":38,"isoforms":0,"proteomes":1,"sets":6,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":3,"profile":1,"pfam":3,"cdd":4,"ncbifam":6,"hamap":2,"panther":1,"prints":1,"prosite":1,"interpro":14},"proteome":1,"taxonomy":1,"similar_proteins":3803}}}