{"metadata":{"accession":"A0A2U3W1U0","id":"A0A2U3W1U0_ODORO","source_organism":{"taxId":"9708","scientificName":"Odobenus rosmarus divergens","fullName":"Odobenus rosmarus divergens (Pacific walrus)"},"name":"Dehydrogenase/reductase SDR family member 6","description":["NAD(H)-dependent dehydrogenase/reductase with a preference for cyclic substrates. Catalyzes stereoselective conversion of 4-oxo-L-proline to cis-4-hydroxy-L-proline, likely a detoxification mechanism for ketoprolines. Mediates the formation of 2,5-dihydroxybenzoate (2,5-DHBA), a siderophore that chelates free cytoplasmic iron and associates with LCN2, thereby regulating iron transport and homeostasis while protecting cells against free radical-induced oxidative stress. The iron-siderophore complex is imported into mitochondria, providing an iron source for mitochondrial metabolic processes in particular heme synthesis. May act as a 3-hydroxybutyrate dehydrogenase"],"length":245,"sequence":"MGRLDGKVIVLTAAAQGIGRAAALAFAREGAKVIATDINESKLQELEEYPGIQIRTLDVTKKKQIDQFANEIERLDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSIKGVMNRCVYSATKAAVIGLTKSVATDFIQQGIRCNCVCPGTVDTPSLQERIQARPNPEEARNCFLKRQKTGRFATPEEIALLCVYLASDESAYVTGNPVIIDGGWSL","proteome":"UP000245340","gene":"BDH2","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"ff1cec7cb7eee88f7c3ec2b2277c3a1762c3bf68","counters":{"domain_architectures":518272,"entries":12,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"cdd":1,"pfam":1,"panther":1,"prints":2,"prosite":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":518272}}}