{"metadata":{"accession":"A0A2K6MN43","id":"A0A2K6MN43_RHIBE","source_organism":{"taxId":"61621","scientificName":"Rhinopithecus bieti","fullName":"Rhinopithecus bieti (Black snub-nosed monkey)"},"name":"Small RNA 2'-O-methyltransferase","description":["Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis"],"length":424,"sequence":"MEENNLQCSSVVDGNFEEVPRETAIQFKPPLYRQRYQFVKNLVDQHEPKKVADLGCGDTSLLRLLKVNPCIELLVGVDINEDKLRWRGDSLAPFMGDFLKPRDLNLTITLYHGSVVERDSRLLGFDLITCIELIEHLDSGDLARFPEVVFGYLSPSMIVISTPNSEFNPLFPSVTLRDSDHKFEWTRMEFQTWALYVANRYDYSVEFTGVGEPPAGAENVGYCTQIGIFHKNGGKATEACVSEQHDQHVYKARQGLTMLPRLVLIFHPQAVLLPHLPKMLRLQVFTTSYPSLQQERFFKLVLVNEVSQQVESLRVSHLPRRKEQDGERGDKPKDIGGSKAPVPCFGPVFTEVEKAKIENSPKPFCVGDKFFVPLQRLLAYPRLNRLCANEEMMRSVIADSIPLSSDGSAVVADLCNYFDEQFEF","proteome":"UP000233180","gene":"HENMT1","go_terms":[{"identifier":"GO:0008171","name":"O-methyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008173","name":"RNA methyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0001510","name":"RNA methylation","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"e44e906cbea566d2a398978fae3bffc8ca67eb47","counters":{"domain_architectures":158,"entries":8,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":2,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":158}}}