{"metadata":{"accession":"A0A2I3SKP0","id":"A0A2I3SKP0_PANTR","source_organism":{"taxId":"9598","scientificName":"Pan troglodytes","fullName":"Pan troglodytes (Chimpanzee)"},"name":"Zinc finger CCCH domain-containing protein 14","description":["RNA-binding protein involved in the biogenesis of circular RNAs (circRNAs), which are produced by back-splicing circularization of pre-mRNAs. Acts by binding to both exon-intron boundary and 3'-UTR of pre-mRNAs to promote circRNA biogenesis through dimerization and the association with the spliceosome. Required for spermatogenesis via involvement in circRNA biogenesis. Regulates the pre-mRNA processing of ATP5MC1; preventing its degradation. Also binds the poly(A) tail of mRNAs; controlling poly(A) length in neuronal cells"],"length":282,"sequence":"MRMSSKFPSPPLPIFLPPEPVDLGSITSSSCSLNEPDNISHRLRKISADINEIKGMRAAILTVEANLFDLNVRVSKNEAKISSLEVKMNEYSTTYECNRQFEDQEEDTESQSRTTDVKIIGFLRNVEKAEMSELSVAQKPEKLLERCKYWPACKNGDECAYHHPISPCKAFPNCKFAEKCLFVHPNCKYDAKCTKPDCPFTHVSRRIPVLSPKPAVAPPAPPSSSQLCRYFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTINVPPRHALKWIRPQTSE","proteome":"UP000002277","gene":"ZC3H14","go_terms":[{"identifier":"GO:0046872","name":"metal ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008143","name":"poly(A) binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0043488","name":"regulation of mRNA stability","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"a972a1612e2e69965f45f9d830c28aa07f99643a","counters":{"domain_architectures":1802,"entries":8,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"profile":1,"smart":1,"cathgene3d":2,"pfam":1,"panther":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":1802}}}