{"metadata":{"accession":"A0A2I0LYD4","id":"A0A2I0LYD4_COLLI","source_organism":{"taxId":"8932","scientificName":"Columba livia","fullName":"Columba livia (Rock dove)"},"name":"Platelet-derived growth factor (PDGF) family profile domain-containing protein","description":["Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin"],"length":258,"sequence":"MTLLTTQLEGNVADSSALEQSSPHSLQVLWAQLIKFLEVYERSFCRTIETLVDIFQEYPDEVEYIFKPSCVPLMRCAGCCGDEGLECVPVDVYNVTMEIMRIKPHQSQHIAHMSFLQHSKCDCRPKKDVKNKQEKWAQKPRSDGHSFIPQTWSLHDPQPWQSFVMLYPESGKSRRVCPTRMDSRKSKRGKGKGQKRKRKKGRYKPPSFHCEPCSERRKHLFVQDPQTCKCSCKFTDSRCKSRQLELNERTCRCEKPRR","proteome":"UP000053872","gene":"VEGFA","go_terms":[{"identifier":"GO:0008083","name":"growth factor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0008201","name":"heparin binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"82f9ea6e740d23cb5b8e79210b0b91e134330f7d","counters":{"domain_architectures":415,"entries":17,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":2,"profile":1,"smart":1,"cdd":1,"pfam":2,"panther":1,"prosite":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":415}}}