{"metadata":{"accession":"A0A2A2JJF4","id":"A0A2A2JJF4_9BILA","source_organism":{"taxId":"2018661","scientificName":"Diploscapter pachys","fullName":"Diploscapter pachys"},"name":"Ribonuclease","description":["Endonuclease that specifically degrades the RNA of RNA-DNA hybrids","Scramblase that mediates the translocation of glucosaminylphosphatidylinositol (alpha-D-GlcN-(1-6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol, GlcN-PI) across the endoplasmic reticulum (ER) membrane, from the cytosolic leaflet to the luminal leaflet of the ER membrane, where it participates in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a lipid glycoconjugate involved in post-translational modification of proteins. Can also translocate 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) (phosphatidylinositol or PI), as well as several other phospholipids (1,2-diacyl-sn-glycero-3-phosphocholine, 1,2-diacyl-sn-glycero-3-phosphoethanolamine), and N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI) in vitro"],"length":776,"sequence":"MSIETSDSIQRGPTWNGFAEREPCVLGIDEAGRGPVLGPMVYGCAVSPLSQAEQLKALGVADSKQLTEDKREKIFKKMESDEQTQGVVTYALKSLSPQYISCSMLKRAKFSLNEISHSAAIALIRDALSAGINVVEIKVDTVGPKATYQSKLESIFPGISITVTEKADSLFPVVSAASIAAKVTRDRSLRDWAFAEKNVKVPKEGWGSGYPGDPTTKKFLQESVDPVFGYSGLTKMGIFSISNLITVVFIGYMSHSMYDLYTLLTPKECTSSTRHCLKPKFSPDKDGLFPPLQLRVYVSKSERELGSLLFSTKDFQLAWEFEKKVNLTLTPAMRRNSTKIFAQAIFLPNDYSHDQPFQGPWYETKIDSMIVYQPPIPETFNLMQTDEQKKIEEKMSKEKPVPHFRSVLPLAASKDPVNFDLALMSNMIRGLISTDREDSSKYMPFIMIDTLSMRSKDLVELKSTTEQIELSIHYRPVSMAKYLLLAHMGVACSQVKQMGFGEKDVDQIKSLFVDTNVYLIGATFVVSALHLLFDILSFKNDISFWRAKRTMVGISTKALLWKVFSYTVLFFHLFEENTSLLVVIPMGVSALIEYWKAIKAFKISFSISGGIKFGEHSKDEVEPEQLDNQAMKYLSYLMAPLCIGGAIYSLAYVPHKSWRSWVLESLANGIYAFGFLFMLPQLFLNYKLKSVAHLPWRAFMYKAFNTFIDDLFAFIITMPTAHRIACFRDDVVFVIYLYQKWLYPVDYKRVNEFGQSGDENGDDKKSEKSEKLKKEE","proteome":"UP000218231","gene":"WR25_04322","go_terms":[{"identifier":"GO:0003676","name":"nucleic acid binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004523","name":"RNA-DNA hybrid ribonuclease activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016070","name":"RNA metabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"083f97125815808f1acb9f3fa86d3e0066456744","counters":{"domain_architectures":18,"entries":15,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"profile":1,"ssf":1,"pfam":2,"cdd":1,"ncbifam":1,"panther":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":18}}}