{"metadata":{"accession":"A0A287B2D7","id":"A0A287B2D7_PIG","source_organism":{"taxId":"9823","scientificName":"Sus scrofa","fullName":"Sus scrofa (Pig)"},"name":"Dolichol phosphate-mannose biosynthesis regulatory protein","description":["Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. May act by regulating the GPI-GNT complex","Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization"],"length":84,"sequence":"MATGTDQVVGLGLVAVSLIIFTYYTTWVILLPFIDSQHVIHKYFLPRAYAVAIPLAAGLLLLLFVGVFITSVMLKSQKVTKKAQ","proteome":"UP000008227","gene":"DPM2","go_terms":[{"identifier":"GO:0030234","name":"enzyme regulator activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0180047","name":"dolichol phosphate mannose biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005789","name":"endoplasmic reticulum membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"7878cb2ac137a5cc1fbe88804d5d3b7ed8b7c749","counters":{"domain_architectures":2983,"entries":3,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"panther":1,"pfam":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":2983}}}