{"metadata":{"accession":"A0A218U8V2","id":"A0A218U8V2_9PASE","source_organism":{"taxId":"40157","scientificName":"Lonchura striata","fullName":"Lonchura striata (white-rumped munia)"},"name":"Lysophospholipase-like protein 1","description":["Palmitoyl thioesterase that catalyzes depalmitoylation of CGAS and KCNMA1. Acts as a regulator of innate immunity by mediating depalmitoylation of CGAS, thereby preventing CGAS homodimerization and cyclic GMP-AMP synthase activity. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site"],"length":236,"sequence":"MAAPAALQRSVVSPAGRHTASLIFLHGSGDTGQGARAWIKQILNQDMAFQHIKVIYPTAPARPYTPMKGAFSNVWFDRYKICNDCPEHIESIDSMCQGLTDLINDEVKNGIAKNRILIGGFSMGGGMAMHLAFRFHQDLAGVFALSSFLNKDSAVYQALKKNENALPELFQCHGTADDLVLYSWGEETNKMLKSLGVSTSLHTFPNLNHELNRTEIEKLKSWIVKKLPVEAPKANE","proteome":"UP000197619","gene":"LYPLAL1","go_terms":[{"identifier":"GO:0016787","name":"hydrolase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"480047bf4951157f05965ce351dd9692ddf52b46","counters":{"domain_architectures":32952,"entries":7,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"pfam":1,"ssf":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":32952}}}