{"metadata":{"accession":"A0A1G4IFS9","id":"A0A1G4IFS9_TRYEQ","source_organism":{"taxId":"5694","scientificName":"Trypanosoma equiperdum","fullName":"Trypanosoma equiperdum"},"name":"Deoxyhypusine hydroxylase","description":["Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function","Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor"],"length":317,"sequence":"MDQDLSVCEQEYRKLLDPEEPLFSRTRELYRLKESILRTPAGVHVLAKAVDTTNSVLLQHELVYNLGQSAMVEACPHLERFIRAVGKYDIVTRHEAVEALGAIGDPACIPLLRHFMEPANEPEAAIRESCELALKRIEMLEEKGKEAVGPAANCPFVSIDPAPAFNGTNIGGSAPYTVSELENLLCDTTGAVSLWLRYQAMFTLRNIGTPEAVAALSRALRQDNTSALLRHEVAFVLGQLEHPASQPALLDALRDEHEAPMVRHEAAEALGAIADPKTLPALEEYAKHKEAIVRDSCVVALEMHKYWSQFNNQRIQH","proteome":"UP000195570","gene":"TEOVI_000282800","go_terms":[{"identifier":"GO:0019135","name":"deoxyhypusine monooxygenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008612","name":"peptidyl-lysine modification to peptidyl-hypusine","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"002112098362c4876aa1cc5573403d54b5b94ca1","counters":{"domain_architectures":63,"entries":13,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"smart":1,"ssf":1,"pfam":2,"profile":1,"hamap":1,"panther":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":63}}}