{"metadata":{"accession":"A0A146X0N4","id":"A0A146X0N4_FUNHE","source_organism":{"taxId":"8078","scientificName":"Fundulus heteroclitus","fullName":"Fundulus heteroclitus (Killifish)"},"name":"Rab GDP dissociation inhibitor","description":["Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP","Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes"],"length":442,"sequence":"MQEYDVIVLGTGIKECVLSGLMSLSGKKVLHIDKNSYHGGESTSISPLEELYRRFKVPGPPKSIRRGKEWNVDLVPKFFLATGQLVQILVHTEVTRYLDFKVVEGSYVFKAGKVHKVPASEEDAQSSDLMGMFDKRRFKKLLHFVLNFDIRNPRTHQDVDPEKTTSRELFTRFDLGQDVIEFTGHAIALHSDESYLDRPCLETINRIRLYCESLSRHHLSPYLYPLYGLGELPQGFARLSAEYGGTFLLNKPVDEIVMDSGKVKAVKSDGKIFHCKQLICDPSYVPNRVRKVGRVIRVICLLNHPVKNTHEASSCQIIIPQTQLSRKSDIYICVVSYSHSLASDGMYIATVSTTVETNNPEKEVEPALELLEPIMQKFVSITNLLVPNEDGRKSQIFVSRSYDATNHFDSECEDIKDMYRRITGTELCFGRPRNLSHNSDDD","proteome":null,"gene":null,"go_terms":[{"identifier":"GO:0005092","name":"GDP-dissociation inhibitor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007264","name":"small GTPase-mediated signal transduction","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005093","name":"Rab GDP-dissociation inhibitor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0015031","name":"protein transport","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"bf4a0619627864712015915d155a6b211ace67a2","counters":{"domain_architectures":9748,"entries":11,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":3,"panther":1,"pfam":1,"prints":2,"interpro":3},"proteome":0,"taxonomy":1,"similar_proteins":9748}}}