{"metadata":{"accession":"A0A133VAA6","id":"A0A133VAA6_9EURY","source_organism":{"taxId":"1698276","scientificName":"candidate division MSBL1 archaeon SCGC-AAA261G05","fullName":"candidate division MSBL1 archaeon SCGC-AAA261G05"},"name":"Type 2 DNA topoisomerase 6 subunit A","description":["Relaxes both positive and negative superturns and exhibits a strong decatenase activity"],"length":356,"sequence":"MPKKKKTKDPRKEAKKKLVEFGSEVLESIKKTEPPRMKVPSRSTSNILYDDKNRFYTLGEKVGTRTAANMRQVKKFAQTMCAAEFCRSLIDADKTATLREMYYTSEGWETGGFSDQGRSDKVVEDLESAFGVKREDLGLLPEEDGASIFGELVVDEGGMEVNATEAGRAGYTIPPTMNDVEFLECDAKKVLAVETMGMYHRLVQEEAWDQFDALVVALKGQPARATRRFLKRANEELGLPIHLFTDGDPFGFHIAMVVISGSAKLAYINHELAVPDAKFIGVTASDIEDYDLPTDKLRETDVKRLKQLLDDPRYSDDTWQSEIKKMLKIGKKAEQQAFSKYGLDYVVNEYLPSKLS","proteome":"UP000070405","gene":"top6A","go_terms":[{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005694","name":"chromosome","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006259","name":"DNA metabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0003918","name":"DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006265","name":"DNA topological change","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"fc27503cfdf11c18102086aecab4e23d3db9c5ab","counters":{"domain_architectures":1253,"entries":19,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"profile":1,"ssf":1,"pfam":3,"cdd":1,"panther":1,"hamap":1,"prints":2,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":1253}}}