{"metadata":{"accession":"A0A133V2W7","id":"A0A133V2W7_9EURY","source_organism":{"taxId":"1698270","scientificName":"candidate division MSBL1 archaeon SCGC-AAA259M10","fullName":"candidate division MSBL1 archaeon SCGC-AAA259M10"},"name":"Digeranylgeranylglycerophospholipid reductase","description":["Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. Is also probably able to reduce double bonds of geranyl groups in CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol and archaetidylserine, thus acting at various stages in the biosynthesis of archaeal membrane lipids"],"length":394,"sequence":"MPKSEYDVIVVGAGPAGATAAKAAAENGADVLMVDKRRELGVPVQCGEALSEEILKKLDIDPDPRWAINKINRAMLVSPSGKPVEIKQKKSAKIGYILDRKVFDKYLAILAIRSGADIRIDTFVNGLVKENGEINGVTLQGKKGEEIRSDLIIAADGVMSRVARWAGFDTTLGMEDIESGAQFKMVNVDVEEKSMMKFYFGNEIAPGGYIWIFPRGDDIANVGIGVMPKKAEKKSIEYLKDFISARPDLENGRIIEINVGGVPVSGPIEKTYGDDIMIVGDAARQVNALTGGGIDWSMHAGNIAGEVAARAVAEGDTSEGNLKEYEDRWRDEMGDSLNKYYKGKEVLMDLSDGDLDDLADSLQDVDFEKISLTSMLRVIMKANPKLMIKLRGLL","proteome":"UP000070341","gene":"AKJ40_00420","go_terms":[{"identifier":"GO:0016491","name":"oxidoreductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016628","name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0045550","name":"geranylgeranyl reductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008610","name":"lipid biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"ad7e51e2a62958492478fc28c8c0d166e1201da1","counters":{"domain_architectures":135,"entries":15,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"pfam":2,"cathgene3d":2,"hamap":1,"panther":1,"ncbifam":1,"prints":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":135}}}