{"metadata":{"accession":"A0A0N9N577","id":"A0A0N9N577_9EURY","source_organism":{"taxId":"1604004","scientificName":"Halanaeroarchaeum sulfurireducens","fullName":"Halanaeroarchaeum sulfurireducens"},"name":"Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein","description":["Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function"],"length":523,"sequence":"MRVLGIEGTAWAASAAVYDNETDDVFIETDPYQPESGGIHPREAAEHMREAIPSVVETALSAATGPIDAVAFSRGPGLGPCLRVVGTAARALAQSLDVSLVGVNHMVAHLEIGRHRSGFDSPVCLNVSGANAHVLGYRNGRYRVLGETMDTGAGNAIDKFTRHVGWTHPGGPKVEEAANDGEYVDLPYVVKGMDFSFSGIMSAAKQAYDDGVPVEDVSRGLQETMFAMLTEVSERALSLTGRDELVVGGGVAQNERLQEMLREMADQRGANLHVPDPRFLGDNAGMIAVLGAMMAAAGETVAVEDSGIDADYRPDQVPVTWRPGEPPAPGGDRSDEIRGAEAVVTVEDGLVTKRRVPKTYRHPALDERLRRERTVEEARLTHDARRAGVPTPVLRDVDVRESTLVVEFVGERDLRDAVGTTRVQSVGEHLATIHGEGIVSGDPTTRNVRVDGPRTYLIDFGLGYYSQDVEDHAMDLHVFEQSLRGTADEPEPLVSAFEGAYADAGQDAVLDQLRAIEGRGRYQ","proteome":null,"gene":"HLASA_1966","go_terms":[{"identifier":"GO:0002949","name":"tRNA threonylcarbamoyladenosine modification","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0000408","name":"EKC/KEOPS complex","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0004222","name":"metalloendopeptidase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008270","name":"zinc ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004674","name":"protein serine/threonine kinase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"7b9abc2a1639562e73a52cbc6da89a4b5eb7adec","counters":{"domain_architectures":61776,"entries":23,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"cathgene3d":3,"panther":1,"hamap":2,"pirsf":1,"ncbifam":5,"pfam":1,"prints":1,"interpro":7},"proteome":0,"taxonomy":1,"similar_proteins":61776}}}