{"metadata":{"accession":"A0A0L0CBN7","id":"A0A0L0CBN7_LUCCU","source_organism":{"taxId":"7375","scientificName":"Lucilia cuprina","fullName":"Lucilia cuprina (Green bottle fly)"},"name":"Mediator of RNA polymerase II transcription subunit 16","description":["Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors"],"length":785,"sequence":"MTILYKVQNPGGNKDGYLLPNCVLCKISCKNVVAFCVHQGLQSNIYVCDIVTPWQSFKLNTCKNIVTVLEWNQTGEFLMAGYKNGICEIWSTKQNSINSWILLYKANLPSEEILSAKFFHNGKRVYFNTHKKDLQAYSDKFERMDFRPSMTHFGNTPVEGVFVLTSSGLLGAFIIPKLLPPADSLTNGSYVATDLNVHTHSIGLSRSYITHSSVTWCPTGYFSVAVNSWHEPLINCYKVNVERDAEESVNIKCNAVASIFLPKGEVESKQVSHIRWRTINGEEILFVVYDCLEGSFIEQWILTKKHQAVHKLLQKNKSDFVQWEQWENSAKLALSSRVCDVCITKLPSEAMLIFATLRDNSVQVLELGLKKIGSTVFERMAEEQHRMPCKLLTADVTYLNQLLVLFDNFGQMYAMQVPTNHYDKNYKMNPLSLPVALLEYSIVTGIDASDVIMLNLPNLEMLAEKLTENFTRQHNFTRQFYYSNFLSLKSNLCRIQSKQQDFDNLITLHSISIAFKSLLRPSDLSSQDKGPAENLSMILSDPNPQYNDVDKVLCVLDAKDYTVEPATLQSLQQLIQWVADLGLNILNKLPDEIMKSKFNKKHGYDISRDMIAISSIRELLVMIRIWGLLNPQCLPIYTKSIETFDVLPVLFRLLTRLYQNPNEPDDGLLDDCSVLSTQVLIPNRHLNTPTTLLNSHATTKLFPFVFQTSVEPLALQDIHYDEVVFANSTRDDVSNLHLGSKVKSVRKCIRCGFINNINRNTKTSALKAWCQRWEYCHCGGFWLTT","proteome":"UP000037069","gene":"MED16","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016592","name":"mediator complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"606ae1964762319d2de1a6cbc598829cdd9f7e40","counters":{"domain_architectures":735,"entries":12,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":3,"panther":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":735}}}