{"metadata":{"accession":"A0A096MEQ2","id":"A0A096MEQ2_POEFO","source_organism":{"taxId":"48698","scientificName":"Poecilia formosa","fullName":"Poecilia formosa (Amazon molly)"},"name":"mRNA decay activator protein ZFP36","description":["Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs"],"length":328,"sequence":"WSSNIWSQAPVSDKKQLSFRPDRSMSLTEPSSSLLPSIGHLKGLEPFPPSPATTVAPPPGFPPSSNLPAQVPPMLSSNRYKTELCRGYQESGTCKYGSKCQFAHGEAELRGMFRHPKYKTEPCRTFYNFGYCPYGSRCHFIHEEKISGGPLPSAKFQQQQNPSASGSHNPRHQLRQSVSFAGFMGPSRSSSPPSFSSLFNDPNLGFTRAPSVSPPPADLLSPVFGDSVQRETSAFQFGSHQTRTSTGNIPLILEPKPTRCVCNHGNNFSNSIGSTGGFTRSAGLQRFSSEDSLEDSYSSSSSSGSESPIFDGSATKRLTVFERLSLSD","proteome":"UP000028760","gene":null,"go_terms":[{"identifier":"GO:0046872","name":"metal ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003729","name":"mRNA binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"2d07578e935b1cfff44cc1653ceafa437332d212","counters":{"domain_architectures":7288,"entries":9,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"smart":1,"profile":1,"panther":1,"pfam":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":7288}}}