{"metadata":{"accession":"A0A091MLH1","id":"A0A091MLH1_9PASS","source_organism":{"taxId":"57068","scientificName":"Acanthisitta chloris","fullName":"Acanthisitta chloris (rifleman)"},"name":"NF-kappa-B inhibitor alpha","description":["Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals. On cellular stimulation by immune and pro-inflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription"],"length":239,"sequence":"SFLHLAIIHEEKALSLEVIQQAAGDRAFLNFQNNLSQTPLHLAVITDQPEIAEHLLKAGCDLEIRDFRGNTPLHIACHQGSLRSVSVLTQYCQPQHLLAVLQAANYNGHTCLHLASIQGYLAIVEYLLSLGADVNAQEPCNGRTALHLAVDLQNSDLVSLLVKHGADVNKVTYQGYSPYQLTWGRDNSSIQEQLKQLTTADLQMLPESEDEESSESEPEFTEDELIYDDCIIGGRQLAF","proteome":"UP000053537","gene":"N310_01585","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":true,"in_alphafold":true,"in_bfvd":false,"ida_accession":"213489c9c2487618f3f125634eb87cb17253af2b","counters":{"domain_architectures":1108,"entries":12,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":2,"smart":1,"profile":2,"panther":1,"prints":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":1108}}}