{"metadata":{"accession":"A0A080WMA9","id":"DHAS_TRIRC","source_organism":{"taxId":"559305","scientificName":"Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892)","fullName":"Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot fungus)"},"name":"Aspartate-semialdehyde dehydrogenase","description":["Catalyzes the NADPH-dependent formation of L-aspartate 4-semialdehyde (L-ASA) by the reductive dephosphorylation of 4-phospho-L-aspartate (PubMed:26869335). Mediates the second step in the biosynthesis of amino acids that derive from aspartate (the aspartate family of amino acids), including methioinine and threonine, the latter of which is a precursor to isoleucine (PubMed:26869335)"],"length":362,"sequence":"MATPSKKRCGVLGATGAVGTRFILLLSQHPLLELVAVGASDRSSGKKYRDAVRWKQSAPMPAKVADLTVRCCDPAEFSDCDIIFSGLDPDAAGEIEMAFLKANFAVFSNAKNYRLDPMVPLVVPLVNAGHIDVIPAQRKHFGLDKGMLVCNSNCAVVGLVVPAKALIQKFGPIESVSMVTMQAVSGAGYPGVSSMDIFDNIVPYIPGEEGKISSEARKILGDLNSDLAGFSDQKPLQISVACNRVPVLDGHTVCASLRFVNRPPPTASQVREALREYKPEVQTLGCPSAPKMSIHVMDEVDRPQPRLDRETEGGYACTVGRIREDDSDVFDIQFVALSHNTVLGASGSSILNAESAILKGFV","proteome":"UP000008864","gene":"TERG_03598","go_terms":[{"identifier":"GO:0016620","name":"oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051287","name":"NAD binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0046983","name":"protein dimerization activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008652","name":"amino acid biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0050661","name":"NADP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004073","name":"aspartate-semialdehyde dehydrogenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006520","name":"amino acid metabolic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"f9fead37a78f3f17b34aebdc17f03c19c953c120","counters":{"domain_architectures":32953,"entries":20,"isoforms":0,"proteomes":1,"sets":2,"structures":2,"taxa":1,"dbEntries":{"cdd":2,"smart":1,"ssf":2,"cathgene3d":2,"pfam":2,"panther":1,"ncbifam":2,"pirsf":1,"prosite":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":32953}}}