{"metadata":{"accession":"A0A060Y4B2","id":"A0A060Y4B2_ONCMY","source_organism":{"taxId":"8022","scientificName":"Oncorhynchus mykiss","fullName":"Oncorhynchus mykiss (Rainbow trout)"},"name":"Ribonuclease H1","description":["Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II"],"length":304,"sequence":"MFRLPVFYSIIHRAVCIGTEEMVKGKFFYAVRKGLNPGVYQTWDECKKQIDKFPHASYKKFAAEKDAWAFVRGKATSITPEVSEGTSYEATLPRRAPEALEYIPIGQKRHYNHVEEEEKEVVSPAKRAKPSQEAFQDSCASSKSSDGFTYMGDAVVVYTDGCCSGNGKPGARAGIGVYWGRDHPLNVAEPLDGRQTNQRAELQARTAACKALEQAKEMDIKKLVLYTDSKFTINGVTSWVKNWKLNNWRLKSGGPIINREDFEKLDKLNEELKVVWLHIPGHAGYLGNEEADRLSREGAAKRSH","proteome":null,"gene":"GSONMT00055645001","go_terms":[{"identifier":"GO:0003676","name":"nucleic acid binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004523","name":"RNA-DNA hybrid ribonuclease activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000287","name":"magnesium ion binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"08f2b2fe543027b53a1b0199bdaeb1e8940527c5","counters":{"domain_architectures":5019,"entries":18,"isoforms":0,"proteomes":0,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"pfam":2,"ssf":2,"profile":1,"cdd":1,"panther":1,"pirsf":1,"interpro":8},"proteome":0,"taxonomy":1,"similar_proteins":5019}}}