{"metadata":{"accession":"SFLDF00347","entry_id":null,"type":"family","go_terms":null,"source_database":"sfld","member_databases":null,"integrated":"IPR024017","hierarchy":null,"name":{"name":"KxxxW cyclic peptide maturase (StrB-like)","short":"KxxxW_cyclic_peptide_maturase_"},"description":[{"text":"<p>Proteins in this family all perform a KxxxW cyclisation of a peptide via a radical SAM mechanism [[cite:PUB00055042],[cite:PUB00135971]].\nCuratorNotes Contains a SPASM domain</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00055042":{"PMID":17921293,"ISBN":null,"volume":"189","issue":"24","year":2007,"title":"Control of the transcription of a short gene encoding a cyclic peptide in Streptococcus thermophilus: a new quorum-sensing system?","URL":null,"raw_pages":"8844-54","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Ibrahim M","Guillot A","Wessner F","Algaron F","Besset C","Courtin P","Gardan R","Monnet V."],"DOI_URL":"http://dx.doi.org/10.1128/JB.01057-07"},"PUB00135971":{"PMID":25901822,"ISBN":null,"volume":"7","issue":"5","year":2015,"title":"Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink.","URL":null,"raw_pages":"431-437","medline_journal":"Nat Chem","ISO_journal":"Nat Chem","authors":["Schramma KR","Bushin LB","Seyedsayamdost MR."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":0,"interactions":0,"matches":12,"pathways":0,"proteins":12,"proteomes":0,"sets":0,"structural_models":{"alphafold":12,"bfvd":0},"structures":3,"taxa":26},"entry_annotations":{"hmm":0,"logo":0},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}