{"metadata":{"accession":"PF31169","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR061891","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8830)","short":"DUF8830"},"description":[{"text":"<p>This entry represents a domain of approximately 100 residues found in small uncharacterized proteins in Streptomyces and related Actinomycetes. These proteins typically consist of this single domain only. Foldseek analysis suggests weak structural similarity to DUF6204 ([pfam:PF19707]). The function of this domain remains to be determined.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":864,"pathways":0,"proteins":864,"proteomes":859,"sets":0,"structural_models":{"alphafold":372},"structures":0,"taxa":940},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":19,"alignment:full":419},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}