{"metadata":{"accession":"PF31120","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR061878","hierarchy":null,"name":{"name":"Family of unknown function (DUF8817)","short":"DUF8817"},"description":[{"text":"<p>This is a family of fungal uncharacterised sequences of unknown function. Some members are annotated as related to antimicrobial resistance. There are two highly conserved motifs FYxxLGF and GxPR.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0104","name":"Glyoxalase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":14,"interactions":0,"matches":2457,"pathways":0,"proteins":2442,"proteomes":2136,"sets":1,"structural_models":{"alphafold":1447},"structures":11,"taxa":3226},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":75,"alignment:full":1062},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"1xrk","name":"Crystal structure of a mutant bleomycin binding protein from Streptoalloteichus hindustanus displaying increased thermostability"}}}