This entry represents a C-terminal domain of approximately 125 residues found in multi-domain proteins that contain the DUF7408 domain ([pfam:PF24157]). Structural similarity searches identify this as a member of the galactose-binding domain-like superfamily. This family is found in Bacillota, particularly Bacillales (including Paenibacillus and Bacillaceae) and Clostridia, as well as some Chloroflexota. The function of this domain remains to be determined.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0202","name":"GBD"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":8,"interactions":0,"matches":398,"pathways":0,"proteins":398,"proteomes":365,"sets":1,"structural_models":{"alphafold":260},"structures":0,"taxa":576},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":49,"alignment:full":217},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}