This entry represents a C-terminal domain of approximately 110 residues found in Type IIG restriction-modification enzymes in bacteria. This domain is located C-terminal to the TaqI_C domain ([pfam:PF12950]). The function of this domain remains to be determined.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":14,"interactions":0,"matches":501,"pathways":0,"proteins":501,"proteomes":440,"sets":0,"structural_models":{"alphafold":314},"structures":0,"taxa":995},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":187,"alignment:full":261},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}