{"metadata":{"accession":"PF30795","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR061805","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8744)","short":"DUF8744"},"description":[{"text":"<p>This entry represents a domain of approximately 120 residues found in predicted integral membrane proteins. Some members are annotated as NnrS family proteins. According to STRING, this domain co-occurs with DUF2249 ([pfam:PF10006]). This family is found predominantly in Actinomycetota and Pseudomonadota. The function of this domain remains to be determined.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0714","name":"COX1-like"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":9,"interactions":0,"matches":786,"pathways":0,"proteins":784,"proteomes":766,"sets":1,"structural_models":{"alphafold":515},"structures":0,"taxa":1385},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":36,"alignment:full":460},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}