{"metadata":{"accession":"PF30764","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR061785","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8724)","short":"DUF8724"},"description":[{"text":"<p>This entry represents a bacterial domain of approximately 220 residues. The domain is predominantly found in Actinomycetes, particularly Streptomycetaceae and related species, as well as in Pseudomonadota. In some proteins, this domain is found N-terminal to the MZB domain ([pfam:PF09369]). The function of this domain remains to be determined.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":6,"interactions":0,"matches":1658,"pathways":0,"proteins":1658,"proteomes":1485,"sets":0,"structural_models":{"alphafold":953},"structures":2,"taxa":2909},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":290,"alignment:full":864},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}