This entry represents a family of small uncharacterised proteins of approximately 67 residues. Some family members are annotated as containing NIF11 or DUF1292 domains, although the functional significance of this is unclear as the family is restricted to marine picocyanobacteria (Prochlorococcus, Synechococcus, and Cyanobium species in Synechococcales), which are not nitrogen-fixing organisms. The function of this family remains to be determined.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
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