This entry represents a family of uncharacterised proteins approximately 150 residues in length. Members are found in Cyanobacteriota and in cyanophages. Some members are annotated as putative serine hydroxymethyltransferases but this has not been experimentally verified. The function of this family remains to be determined.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":31,"pathways":0,"proteins":31,"proteomes":29,"sets":0,"structural_models":{"alphafold":17},"structures":0,"taxa":93},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":6,"alignment:full":35},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}