{"metadata":{"accession":"PF30002","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR062939","hierarchy":null,"name":{"name":"DUF6177, N-terminal domain","short":"DUF6177_N"},"description":[{"text":"<p>This entry represents the N-terminal domain of a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000360) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide). It includes a member from the GE81112 biosynthetic gene cluster from Streptomyces sp. L-49973 and appears to be predominantly found in Actinobacteria [[cite:PUB00074314]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00074314":{"PMID":20710026,"ISBN":null,"volume":"285","issue":"43","year":2010,"title":"Insights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster.","URL":null,"raw_pages":"32710-9","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Binz TM","Maffioli SI","Sosio M","Donadio S","Muller R."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M110.146803"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":712,"pathways":0,"proteins":712,"proteomes":518,"sets":0,"structural_models":{"alphafold":323},"structures":0,"taxa":651},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":68,"alignment:full":306},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}