This is a domain of unknown function found in a group of uncharacterised bacterial sequences. This domain is found at the N-terminal of [pfam:PF09839] and may have a fold consisting of three anti-parallel beta-strands followed by alpha-helices of which one is longer than the other two.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":1941,"pathways":0,"proteins":1940,"proteomes":1934,"sets":0,"structural_models":{"alphafold":1142},"structures":0,"taxa":2597},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":47,"alignment:full":759},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}