This entry represents a small protein family found in both bacteria and viruses. Bacterial members are present in Bacillus and related genera (Bacillaceae), whilst viral members are found in bacteriophages (Takahashivirus). One bacterial member is annotated as a putative secreted or membrane protein. AlphaFold structural predictions are available for some members. The function of this protein family remains to be determined.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
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