This entry represents a protein domain found in tailed bacteriophages (Caudoviricetes). The domain is approximately 67-87 amino acids in length and can occur as a single copy or be repeated within proteins. The family is also found in the Deinococcus bacterial genome, likely derived from an integrated prophage. The function of this domain remains to be determined.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
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