This entry represents a small protein found in bacteriophages that infect Firmicutes, particularly Clostridium species. Members of this family are approximately 85 amino acids in length and appear to be single domain proteins. The family is also found in some bacterial genomes, likely derived from integrated prophages. The function of this protein remains to be determined.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":13,"pathways":0,"proteins":13,"proteomes":13,"sets":0,"structural_models":{"alphafold":2},"structures":0,"taxa":49},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":12,"alignment:full":18},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}