{"metadata":{"accession":"PF29207","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR061579","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8509)","short":"DUF8509"},"description":[{"text":"<p>This entry represents a C-terminal domain found in uncharacterised proteins from spirochaetes, predominantly from Treponema and Leptospira species, and some members of Lachnospiraceae. The domain is approximately 90 residues in length. The function of this domain remains</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":296,"pathways":0,"proteins":296,"proteomes":249,"sets":0,"structural_models":{"alphafold":213},"structures":0,"taxa":430},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":75,"alignment:full":163},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}