This entry represents a C-terminal domain found in some glycosyl hydrolase family 2 proteins. This domain follows the N-terminal ([pfam:PF02837]), catalytic ([pfam:PF00703]) and C-terminal ([pfam:PF02836]) domains characteristic of this family. The domain is approximately 170-185 residues in length. These proteins include exo-beta-1,4-galactosidases involved in degrading galactan substituents from plant cell wall polysaccharides. The family is found in diverse bacteria including Bacteroidota and Bacillota. The function of this domain remains to be determined.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
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