This domain is found at the N-terminal of a group of uncharacterised bacterial sequences and it is predicted to adopt a single-stranded right-handed beta-helix with similarity to ice-binding proteins and other adhesive domains. These proteins are usually associated with tandem Ig-like domain, such as [swissprot:A1S2S0] which has five Ig-like domains.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0847","name":"Ice_binding"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":36,"interactions":0,"matches":139,"pathways":0,"proteins":138,"proteomes":132,"sets":1,"structural_models":{"alphafold":43},"structures":0,"taxa":249},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":6,"alignment:full":44},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}