{"metadata":{"accession":"PF28432","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR059437","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8393)","short":"DUF8393"},"description":[{"text":"<p>This immunoglobulin-like (Ig-like) domain is found in a group of uncharacterised proteobacterial proteins. It is often found associated with [pfam:PF13899], [pfam:PF02683] and [pfam:PF11412] and has conserved P, L, F and D residues. Its function is unknown.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0159","name":"E-set"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":9,"interactions":0,"matches":915,"pathways":0,"proteins":915,"proteomes":871,"sets":1,"structural_models":{"alphafold":548},"structures":1,"taxa":1336},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":163,"alignment:full":366},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}