{"metadata":{"accession":"PF26942","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR059337","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8293)","short":"DUF8293"},"description":[{"text":"<p>This domain is found in uncharacterised bacterial proteins. It is predicted to fold into an alpha-helical structure and it is frequently found in combination with [pfam:PF09977] and and [pfam:PF13400] which are likely involved in pilus biogenesis.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":16,"interactions":0,"matches":1005,"pathways":0,"proteins":1005,"proteomes":961,"sets":0,"structural_models":{"alphafold":563},"structures":0,"taxa":1367},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":37,"alignment:full":418},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}