{"metadata":{"accession":"PF26935","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR059330","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8286)","short":"DUF8286"},"description":[{"text":"<p>This domain is ubiquitously found in uncharacterised proteins. It is found in combination with different domains and give the AlphaFold prediction either associates with another part of th polypeptide chain or with another molecule.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":12,"interactions":0,"matches":298,"pathways":0,"proteins":297,"proteomes":51,"sets":0,"structural_models":{"alphafold":218},"structures":11,"taxa":183},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":18,"alignment:full":324},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}