This domain is found in uncharacterised bacterial proteins. It contains a two pair of highly conserved cysteine residues that may be involved in metal coordination. It is predicted to fold into a structure typical for zinc beta ribbon domains. Some proteins contain multiple copies of this domain.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0167","name":"Zn_Beta_Ribbon"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":39,"pathways":0,"proteins":39,"proteomes":34,"sets":1,"structural_models":{"alphafold":18},"structures":0,"taxa":94},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":13,"alignment:full":18},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}