This domain is found in uncharacterised proteins mainly from Planctomycetia. It contains four pairs of highly conserved cysteine residues that are probably involved in zinc coordination. This domain is predicted to contain two zinc ribbon domains inserted one into the other.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0167","name":"Zn_Beta_Ribbon"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":3,"pathways":0,"proteins":3,"proteomes":3,"sets":1,"structural_models":{"alphafold":3},"structures":0,"taxa":18},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":3},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}